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Summit Therapeutics Inc. conducts clinical programs focusing on Clostridioides difficile infection (CDI) The company's lead product candidate is ridinilazole, an orally administered small molecule antibiotic that is in Phase III clinical trials for the treatment of CDI. The company was founded in 2003 and is based in Cambridge, Massachusetts.
Roles derived from SEC Form 4 filings.
Actuals from SEC filings; YoY vs the year-ago quarter. Analyst estimates & surprise require a data feed (coming soon).
| Line item | FY2020 | FY2021 | FY2022 | FY2023 | FY2024 | FY2025 |
|---|---|---|---|---|---|---|
| Revenue | $860,000.00 | $1.8M | $705,000.00 | $0.00 | $0.00 | — |
| Gross profit | — | — | — | — | — | — |
| Operating income | -$53.2M | -$86.2M | -$72.1M | -$609.6M | -$226.0M | — |
| Net income | -$52.7M | -$88.6M | -$78.8M | -$614.9M | -$221.3M | -$1.1B |
| Diluted EPS | -$0.76 | -$0.67 | -$0.41 | -$0.99 | -$0.31 | -$1.44 |
| Operating cash flow | -$48.1M | -$72.6M | -$41.6M | -$76.8M | -$142.1M | -$322.9M |
| Free cash flow | -$48.5M | -$72.9M | -$42.2M | -$76.9M | -$142.2M | -$323.6M |
| Gross margin | — | — | — | — | — | — |
| Operating margin | -6185.2% | -4764.3% | -10225.4% | — | — | — |
| Net margin | -6127.6% | -4897.8% | -11174.8% | — | — | — |
| Line item | Q2 '24 | Q3 '24 | Q4 '24 | Q1 '25 | Q3 '25 | Q3 '25 | Q4 '25 | Q1 '26 |
|---|---|---|---|---|---|---|---|---|
| Revenue | — | $0.00 | — | — | — | — | — | — |
| Gross profit | — | — | — | — | — | — | — | — |
| Operating income | -$59.6M | -$58.4M | -$65.6M | — | — | — | — | — |
| Net income | -$60.4M | -$56.3M | -$61.2M | -$62.9M | -$565.7M | -$231.8M | -$219.2M | -$189.4M |
| Diluted EPS | -$0.09 | -$0.08 | -$0.08 | -$0.09 | -$0.76 | -$0.31 | -$0.28 | -$0.24 |
| Operating cash flow | -$33.0M | -$30.3M | -$48.7M | -$61.2M | -$66.7M | -$93.1M | -$101.9M | -$122.3M |
| Free cash flow | -$33.1M | -$30.4M | -$48.7M | -$61.6M | -$66.7M | -$93.2M | -$102.1M | -$122.5M |
| Gross margin | — | — | — | — | — | — | — | — |
| Operating margin | — | — | — | — | — | — | — | — |
| Net margin | — | — | — | — | — | — | — | — |
Consensus revenue & EPS estimates and price targets will appear here once a forward-estimates data feed is connected.
| Date | Insider | Type | Shares | Price | Value | Filing |
|---|---|---|---|---|---|---|
| 2026-06-12 | Zanganeh Maky· Co-Chief Executive Officer | Buy | 3,810,000 | $13.12 | $50.0M | filing |
| 2026-06-12 | DUGGAN ROBERT W· Co-Chief Executive Officer | Buy | 3,810,000 | $13.12 | $50.0M | filing |
| 2026-06-04 | DUGGAN ROBERT W· Co-Chief Executive Officer | Buy | 100,000 | $14.60 | $1.5M | filing |
| 2026-06-04 | Zanganeh Maky· Co-Chief Executive Officer | Buy | 100,000 | $14.60 | $1.5M | filing |
| 2026-06-04 | Soni Manmeet Singh· COO and CFO | Buy | 25,000 | $14.46 | $361,500.00 | filing |
| 2026-06-04 | Soni Manmeet Singh· COO and CFO | Buy | 25,000 | $14.43 | $360,750.00 | filing |
| 2025-10-21 | DUGGAN ROBERT W· Co-Chief Executive Officer | Award | 13,980,789 | $18.74 | $262.0M | filing |
| 2025-10-21 | Zanganeh Maky· Co-Chief Executive Officer | Award | 13,980,789 | $18.74 | $262.0M | filing |
| 2025-10-21 | Xia Yu | Buy | 533,617 | $18.74 | $10.0M | filing |
| 2025-10-21 | Zanganeh Maky· Co-Chief Executive Officer | Award | 266,808 | $18.74 | $5.0M | filing |
| 2025-10-21 | DUGGAN ROBERT W· Co-Chief Executive Officer | Award | 266,808 | $18.74 | $5.0M | filing |
| 2025-10-21 | Soni Manmeet Singh· COO and CFO | Award | 53,361 | $18.74 | $999,985.14 | filing |
| 2025-10-21 | Anand Bhaskar· Chief Accounting Officer | Award | 26,680 | $18.74 | $499,983.20 | filing |
| 2025-10-21 | DUGGAN ROBERT W· Co-Chief Executive Officer | Buy | 26,680 | $18.74 | $499,983.20 | filing |
| 2025-10-21 | Zanganeh Maky· Co-Chief Executive Officer | Buy | 26,680 | $18.74 | $499,983.20 | filing |
| 2025-09-11 | Zanganeh Maky· Co-Chief Executive Officer | Buy | 5,000 | $18.07 | $90,350.00 | filing |
| 2025-09-11 | DUGGAN ROBERT W· Co-Chief Executive Officer | Buy | 5,000 | $18.07 | $90,350.00 | filing |
| 2025-09-10 | Zanganeh Maky· Co-Chief Executive Officer | Buy | 333,394 | $17.68 | $5.9M | filing |
| 2025-09-10 | DUGGAN ROBERT W· Co-Chief Executive Officer | Buy | 333,394 | $17.68 | $5.9M | filing |
Latest 19 transactions.
Fundamentals & filings from SEC EDGAR. Prices adjusted for splits & dividends. Not investment advice.