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PTC Therapeutics focuses on the discovery, development, and commercialization of medicines to patients with rare disorders. The company offers Translarna and Emflaza for the treatment of Duchenne muscular dystrophy in the European Economic Area and the United States; Tegsedi and Waylivra for the. treatment of rare diseases in Latin America and the Caribbean. PTC518 is being developed for Huntington's disease.
Roles derived from SEC Form 4 filings.
Actuals from SEC filings; YoY vs the year-ago quarter. Analyst estimates & surprise require a data feed (coming soon).
| Line item | FY2020 | FY2021 | FY2022 | FY2023 | FY2024 | FY2025 |
|---|---|---|---|---|---|---|
| Revenue | $380.8M | $538.6M | $698.8M | $937.8M | $806.8M | $1.7B |
| Gross profit | — | — | — | — | — | — |
| Operating income | -$431.8M | -$374.4M | -$447.4M | -$439.5M | -$302.6M | $866.9M |
| Net income | -$438.2M | -$523.9M | -$559.0M | -$626.6M | -$363.3M | $683.0M |
| Diluted EPS | -$6.64 | -$7.43 | -$7.79 | -$8.37 | -$4.73 | $7.78 |
| Operating cash flow | -$194.1M | -$251.3M | -$356.7M | -$158.4M | -$107.7M | $711.2M |
| Free cash flow | -$211.9M | -$279.5M | -$388.7M | -$186.9M | -$114.2M | $702.3M |
| Gross margin | — | — | — | — | — | — |
| Operating margin | -113.4% | -69.5% | -64.0% | -46.9% | -37.5% | 50.1% |
| Net margin | -115.1% | -97.3% | -80.0% | -66.8% | -45.0% | 39.5% |
| Line item | Q2 '24 | Q3 '24 | Q4 '24 | Q1 '25 | Q2 '25 | Q3 '25 | Q4 '25 | Q1 '26 |
|---|---|---|---|---|---|---|---|---|
| Revenue | $186.7M | $196.8M | $213.2M | $1.2B | $178.9M | $211.0M | $164.7M | $272.6M |
| Gross profit | — | — | — | — | — | — | — | — |
| Operating income | -$40.2M | -$54.5M | -$162.4M | $970.2M | -$35.0M | $3.0M | -$71.3M | $45.0M |
| Net income | -$99.2M | -$106.7M | -$65.9M | $866.6M | -$64.8M | $15.9M | -$134.6M | -$2.8M |
| Diluted EPS | -$1.29 | -$1.39 | -$0.85 | $10.04 | -$0.83 | $0.20 | -$1.63 | -$0.03 |
| Operating cash flow | -$71.5M | -$77.0M | -$30.0M | $870.1M | -$58.3M | -$66.3M | -$34.3M | -$59.0M |
| Free cash flow | -$78.8M | -$77.5M | -$33.8M | $868.4M | -$59.6M | -$69.7M | -$36.6M | -$60.2M |
| Gross margin | — | — | — | — | — | — | — | — |
| Operating margin | -21.5% | -27.7% | -76.2% | 82.5% | -19.5% | 1.4% | -43.3% | 16.5% |
| Net margin | -53.1% | -54.2% | -30.9% | 73.7% | -36.3% | 7.5% | -81.7% | -1.0% |
Consensus revenue & EPS estimates and price targets will appear here once a forward-estimates data feed is connected.
| Date | Insider | Type | Shares | Price | Value | Filing |
|---|---|---|---|---|---|---|
| 2026-07-14 | Gravier Pierre· CHIEF FINANCIAL OFFICER | Sale | 3,494 | $80.35 | $280,742.90 | filing |
| 2026-07-09 | Smith Mary L. | Sale | 10,000 | $90.00 | $900,000.00 | filing |
| 2026-07-09 | Smith Mary L. | Sale | 5,834 | $90.00 | $525,060.00 | filing |
| 2026-07-09 | Smith Mary L. | Option exercise | 10,000 | $42.95 | $429,500.00 | filing |
| 2026-07-09 | Smith Mary L. | Option exercise | 5,834 | $42.95 | $250,570.30 | filing |
| 2026-07-09 | Almstead Neil Gregory· CHIEF TECHNICAL OPS OFFICER | Sale | 2,464 | $90.25 | $222,376.00 | filing |
| 2026-07-09 | Almstead Neil Gregory· CHIEF TECHNICAL OPS OFFICER | Option exercise | 2,464 | $46.54 | $114,674.56 | filing |
| 2026-07-07 | Almstead Neil Gregory· CHIEF TECHNICAL OPS OFFICER | Sale | 11,369 | $89.03 | $1.0M | filing |
| 2026-07-07 | Almstead Neil Gregory· CHIEF TECHNICAL OPS OFFICER | Option exercise | 24,613 | $39.42 | $970,244.46 | filing |
| 2026-07-07 | Almstead Neil Gregory· CHIEF TECHNICAL OPS OFFICER | Sale | 9,288 | $89.44 | $830,718.72 | filing |
| 2026-07-07 | Almstead Neil Gregory· CHIEF TECHNICAL OPS OFFICER | Sale | 3,956 | $87.17 | $344,844.52 | filing |
| 2026-07-06 | Almstead Neil Gregory· CHIEF TECHNICAL OPS OFFICER | Sale | 10,090 | $86.32 | $870,968.80 | filing |
| 2026-07-06 | Almstead Neil Gregory· CHIEF TECHNICAL OPS OFFICER | Sale | 8,786 | $85.35 | $749,885.10 | filing |
| 2026-07-06 | Almstead Neil Gregory· CHIEF TECHNICAL OPS OFFICER | Option exercise | 18,876 | $38.10 | $719,175.60 | filing |
| 2026-07-06 | Almstead Neil Gregory· CHIEF TECHNICAL OPS OFFICER | Sale | 2,474 | $87.03 | $215,312.22 | filing |
| 2026-07-06 | Boulding Mark Elliott· EXEC. VP AND CLO | Option exercise | 2,813 | $46.54 | $130,917.02 | filing |
| 2026-07-06 | Almstead Neil Gregory· CHIEF TECHNICAL OPS OFFICER | Option exercise | 2,474 | $39.42 | $97,525.08 | filing |
| 2026-07-06 | Boulding Mark Elliott· EXEC. VP AND CLO | Option exercise | 2,266 | $39.42 | $89,325.72 | filing |
| 2026-07-06 | Boulding Mark Elliott· EXEC. VP AND CLO | Sale | 1,036 | $84.41 | $87,448.76 | filing |
| 2026-07-06 | Boulding Mark Elliott· EXEC. VP AND CLO | Sale | 833 | $84.41 | $70,313.53 | filing |
| 2026-07-06 | Boulding Mark Elliott· EXEC. VP AND CLO | Sale | 745 | $86.38 | $64,353.10 | filing |
| 2026-07-06 | Boulding Mark Elliott· EXEC. VP AND CLO | Sale | 645 | $85.84 | $55,366.80 | filing |
| 2026-07-06 | Boulding Mark Elliott· EXEC. VP AND CLO | Sale | 601 | $86.38 | $51,914.38 | filing |
| 2026-07-06 | Boulding Mark Elliott· EXEC. VP AND CLO | Sale | 519 | $85.84 | $44,550.96 | filing |
| 2026-07-06 | Almstead Neil Gregory· CHIEF TECHNICAL OPS OFFICER | Sale | 426 | $85.28 | $36,329.28 | filing |
Showing the latest 25 transactions — full history in the linked SEC filings.
Fundamentals & filings from SEC EDGAR. Prices adjusted for splits & dividends. Not investment advice.