Nasdaq
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We are a clinical-stage biopharmaceutical company founded to confront the global brain disease crisis by taking a fundamentally different approach to the way treatments for brain diseases are developed. Our principal executive offices are located at 490 Arsenal Way, Suite 200, Watertown, Massachusetts.
Roles derived from SEC Form 4 filings.
Actuals from SEC filings; YoY vs the year-ago quarter. Analyst estimates & surprise require a data feed (coming soon).
| Line item | FY2022 | FY2023 | FY2024 | FY2025 |
|---|---|---|---|---|
| Revenue | — | — | — | — |
| Gross profit | — | — | — | — |
| Operating income | -$135.9M | -$252.1M | -$263.5M | -$241.2M |
| Net income | -$130.9M | -$235.9M | $243.8M | $236.9M |
| Diluted EPS | -$4.81 | -$3.63 | -$1.53 | -$1.45 |
| Operating cash flow | -$114.9M | -$163.3M | -$182.9M | -$206.4M |
| Free cash flow | -$115.4M | -$163.4M | — | — |
| Gross margin | — | — | — | — |
| Operating margin | — | — | — | — |
| Net margin | — | — | — | — |
| Line item | Q2 '24 | Q3 '24 | Q4 '24 | Q1 '25 | Q2 '25 | Q3 '25 | Q4 '25 | Q1 '26 |
|---|---|---|---|---|---|---|---|---|
| Revenue | — | — | — | — | — | — | — | — |
| Gross profit | — | — | — | — | — | — | — | — |
| Operating income | -$63.8M | -$76.6M | -$62.9M | -$70.9M | -$54.0M | -$57.7M | -$58.5M | -$52.9M |
| Net income | -$58.7M | -$72.5M | $428.8M | -$68.0M | -$52.7M | -$56.8M | $414.4M | -$53.5M |
| Diluted EPS | -$0.37 | -$0.45 | -$0.37 | -$0.42 | -$0.33 | -$0.35 | -$0.35 | -$0.30 |
| Operating cash flow | -$56.2M | -$33.5M | -$50.3M | -$59.4M | -$52.4M | -$46.6M | -$48.0M | -$46.4M |
| Free cash flow | — | — | — | — | — | — | — | — |
| Gross margin | — | — | — | — | — | — | — | — |
| Operating margin | — | — | — | — | — | — | — | — |
| Net margin | — | — | — | — | — | — | — | — |
Consensus revenue & EPS estimates and price targets will appear here once a forward-estimates data feed is connected.
| Date | Insider | Type | Shares | Price | Value | Filing |
|---|---|---|---|---|---|---|
| 2026-02-17 | BERNS PAUL L· See Remarks | Sale | 9,819 | $3.51 | $34,458.80 | filing |
| 2026-02-17 | Aurora Daljit Singh· See Remarks | Sale | 6,165 | $3.56 | $21,916.58 | filing |
| 2026-02-17 | Pinto Joshua· President | Sale | 5,967 | $3.54 | $21,093.35 | filing |
| 2026-02-17 | Milligan Michael Lee· See Remarks | Sale | 1,436 | $3.57 | $5,119.34 | filing |
| 2025-11-11 | Aurora Daljit Singh· See Remarks | Sale | 114,703 | $2.68 | $307,025.52 | filing |
| 2025-10-27 | Burow Kristina | Buy | 1,915,700 | $2.61 | $5.0M | filing |
| 2025-10-27 | ARCH Venture Partners XII, LLC | Buy | 1,915,700 | $2.61 | $5.0M | filing |
| 2025-10-27 | ARCH Venture Partners X, LLC | Buy | 1,915,700 | $2.61 | $5.0M | filing |
Latest 8 transactions.
Fundamentals & filings from SEC EDGAR. Prices adjusted for splits & dividends. Not investment advice.