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OpRegen, a retinal pigment epithelium cell replacement therapy, is in Phase I/IIa clinical trial for the treatment of dry age-related macular degeneration. OPC1, an oligodendrocyte progenitor cell therapy, and VAC2, an allogeneic cancer immunotherapy of antigen-presenting dendritic cells, are in clinical trials to treat non-small cell lung cancer. It also offers Renevia, a facial aesthetics product.
Roles derived from SEC Form 4 filings.
Actuals from SEC filings; YoY vs the year-ago quarter. Analyst estimates & surprise require a data feed (coming soon).
| Line item | FY2020 | FY2021 | FY2022 | FY2023 | FY2024 | FY2025 |
|---|---|---|---|---|---|---|
| Revenue | $1.8M | $4.3M | $14.7M | $8.9M | $9.5M | $14.6M |
| Gross profit | $1.4M | $2.9M | $14.0M | $8.3M | — | — |
| Operating income | -$26.4M | -$49.2M | -$22.5M | -$24.7M | -$21.5M | -$36.6M |
| Net income | -$20.6M | -$43.0M | -$26.3M | -$21.5M | -$18.6M | -$63.5M |
| Diluted EPS | — | — | -$0.15 | -$0.12 | -$0.09 | -$0.28 |
| Operating cash flow | -$19.8M | -$23.6M | $1.1M | -$28.6M | -$23.1M | -$18.9M |
| Free cash flow | -$19.8M | -$23.9M | $646,000.00 | -$29.2M | -$23.7M | -$19.4M |
| Gross margin | 78.9% | 67.2% | 95.0% | 92.5% | — | — |
| Operating margin | -1448.4% | -1133.6% | -153.2% | -276.5% | -226.1% | -251.6% |
| Net margin | -1130.8% | -991.0% | -178.7% | -240.2% | -195.9% | -436.5% |
| Line item | Q2 '24 | Q3 '24 | Q4 '24 | Q1 '25 | Q2 '25 | Q3 '25 | Q4 '25 | Q1 '26 |
|---|---|---|---|---|---|---|---|---|
| Revenue | $1.4M | $3.8M | $2.9M | $1.5M | $2.8M | $3.7M | $6.6M | $1.7M |
| Gross profit | — | — | — | — | — | — | — | — |
| Operating income | -$5.9M | -$3.8M | -$5.1M | -$6.5M | -$19.8M | -$3.8M | -$6.5M | -$7.6M |
| Net income | -$5.8M | -$3.0M | -$3.3M | -$4.1M | -$30.5M | -$29.8M | $851,000.00 | -$4.8M |
| Diluted EPS | -$0.03 | -$0.02 | $0.00 | -$0.02 | -$0.13 | -$0.13 | $0.00 | -$0.03 |
| Operating cash flow | -$5.2M | -$5.8M | -$6.3M | -$4.9M | -$5.5M | -$3.6M | -$4.9M | -$8.1M |
| Free cash flow | -$5.2M | -$5.9M | -$6.7M | -$5.0M | -$5.6M | -$3.6M | -$5.3M | -$8.1M |
| Gross margin | — | — | — | — | — | — | — | — |
| Operating margin | -416.7% | -101.6% | -178.2% | -433.1% | -715.4% | -102.9% | -99.1% | -440.2% |
| Net margin | -409.1% | -80.3% | -114.1% | -275.6% | -1101.8% | -809.0% | 12.9% | -279.0% |
Consensus revenue & EPS estimates and price targets will appear here once a forward-estimates data feed is connected.
| Date | Insider | Type | Shares | Price | Value | Filing |
|---|---|---|---|---|---|---|
| 2026-03-12 | Culley Brian M· President and CEO | Buy | 15,000 | $1.63 | $24,375.00 | filing |
| 2026-02-11 | Culley Brian M· President and CEO | Tax withholding | 12,869 | $1.80 | $23,164.20 | filing |
| 2026-02-11 | Samuel George A. III· General Counsel and Secretary | Tax withholding | 2,502 | $1.80 | $4,503.60 | filing |
| 2026-02-11 | Samuel George A. III· General Counsel and Secretary | Option exercise | 6,075 | — | — | filing |
| 2026-02-11 | Culley Brian M· President and CEO | Option exercise | 31,250 | — | — | filing |
| 2025-12-19 | Culley Brian M· President and CEO | Tax withholding | 334 | $1.68 | $561.12 | filing |
| 2025-12-19 | Samuel George A. III· General Counsel and Secretary | Tax withholding | 65 | $1.68 | $109.20 | filing |
| 2025-12-19 | Culley Brian M· President and CEO | Award | 8,925 | — | — | filing |
| 2025-12-19 | Samuel George A. III· General Counsel and Secretary | Award | 1,735 | — | — | filing |
Latest 9 transactions.
Fundamentals & filings from SEC EDGAR. Prices adjusted for splits & dividends. Not investment advice.