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Kiniksa Pharmaceuticals, Ltd. focuses on discovering, acquiring, developing, and commercializing therapeutic medicines for patients suffering from debilitating diseases with significant unmet medical needs worldwide. Its product candidates include ARCALYST for the treatment of recurrent pericarditis, which is an inflammatory cardiovascular disease. KPL-404 is a monoclonal antibody inhibitor of the CD40- CD154 interaction, a T-cell co-stimulatory signal critical for B-cell maturation.
Roles derived from SEC Form 4 filings.
Actuals from SEC filings; YoY vs the year-ago quarter. Analyst estimates & surprise require a data feed (coming soon).
| Line item | FY2020 | FY2021 | FY2022 | FY2023 | FY2024 | FY2025 |
|---|---|---|---|---|---|---|
| Revenue | — | $38.5M | $220.2M | $270.3M | $423.2M | $677.6M |
| Gross profit | — | — | — | — | — | — |
| Operating income | -$157.4M | -$156.6M | $9.8M | -$25.2M | -$45.6M | $77.2M |
| Net income | -$161.4M | -$157.9M | $183.4M | $14.1M | -$43.2M | $59.0M |
| Diluted EPS | -$2.61 | -$2.30 | $2.60 | $0.20 | -$0.60 | $0.75 |
| Operating cash flow | -$136.5M | -$126.3M | $5.8M | $13.3M | $25.7M | $138.0M |
| Free cash flow | -$136.8M | -$126.7M | $5.7M | $13.2M | $25.4M | $136.4M |
| Gross margin | — | — | — | — | — | — |
| Operating margin | — | -406.4% | 4.4% | -9.3% | -10.8% | 11.4% |
| Net margin | — | -409.7% | 83.3% | 5.2% | -10.2% | 8.7% |
| Line item | Q2 '24 | Q3 '24 | Q4 '24 | Q1 '25 | Q2 '25 | Q3 '25 | Q4 '25 | Q1 '26 |
|---|---|---|---|---|---|---|---|---|
| Revenue | $108.6M | $112.2M | $122.5M | $137.8M | $156.8M | $180.9M | $202.1M | $214.3M |
| Gross profit | — | — | — | — | — | — | — | — |
| Operating income | -$117,000.00 | -$9.7M | -$19.3M | $13.3M | $20.2M | $24.0M | $19.8M | $29.3M |
| Net income | -$3.9M | -$12.7M | -$8.9M | $8.5M | $17.8M | $18.4M | $14.2M | $22.6M |
| Diluted EPS | -$0.06 | -$0.18 | -$0.11 | $0.11 | $0.23 | $0.23 | $0.18 | $0.27 |
| Operating cash flow | $5.2M | -$2.2M | $18.8M | $22.3M | $28.1M | $33.7M | $53.9M | $50.2M |
| Free cash flow | $5.2M | -$2.2M | $18.6M | $22.2M | $27.9M | $33.0M | $53.3M | $50.0M |
| Gross margin | — | — | — | — | — | — | — | — |
| Operating margin | -0.1% | -8.6% | -15.7% | 9.6% | 12.9% | 13.3% | 9.8% | 13.7% |
| Net margin | -3.6% | -11.3% | -7.3% | 6.2% | 11.4% | 10.2% | 7.0% | 10.5% |
Consensus revenue & EPS estimates and price targets will appear here once a forward-estimates data feed is connected.
| Date | Insider | Type | Shares | Price | Value | Filing |
|---|---|---|---|---|---|---|
| 2026-06-01 | Patel Sanj K· CHAIRMAN & CEO | C | 900,000 | — | — | filing |
| 2026-05-29 | BAKER BROS. ADVISORS LP | Award | 6,078 | $0.00 | $0.00 | filing |
| 2026-05-29 | BAKER BROS. ADVISORS LP | Award | 6,078 | $0.00 | $0.00 | filing |
| 2026-05-29 | McCain Tracey L | Option exercise | 2,799 | — | — | filing |
| 2026-05-29 | Malley Thomas | Option exercise | 2,799 | — | — | filing |
| 2026-05-29 | Levy Richard S | Option exercise | 2,799 | — | — | filing |
| 2026-05-29 | Cole G Bradley | Option exercise | 2,799 | — | — | filing |
| 2026-05-29 | Quart Barry D | Option exercise | 2,799 | — | — | filing |
| 2026-05-29 | Popovits Kimberly J | Option exercise | 2,799 | — | — | filing |
| 2026-05-01 | Patel Sanj K· CHAIRMAN & CEO | Sale | 48,565 | $54.02 | $2.6M | filing |
| 2026-05-01 | Paolini John· CHIEF MEDICAL OFFICER | Sale | 37,327 | $53.52 | $2.0M | filing |
| 2026-05-01 | Patel Sanj K· CHAIRMAN & CEO | Option exercise | 48,565 | $30.93 | $1.5M | filing |
| 2026-05-01 | Paolini John· CHIEF MEDICAL OFFICER | Sale | 21,097 | $54.04 | $1.1M | filing |
| 2026-05-01 | Paolini John· CHIEF MEDICAL OFFICER | Option exercise | 58,424 | $10.36 | $605,272.64 | filing |
| 2026-04-30 | Patel Sanj K· CHAIRMAN & CEO | Sale | 2,141 | $54.01 | $115,635.41 | filing |
| 2026-04-30 | Patel Sanj K· CHAIRMAN & CEO | Option exercise | 2,141 | $30.93 | $66,221.13 | filing |
| 2026-04-29 | Patel Sanj K· CHAIRMAN & CEO | Sale | 22,544 | $54.01 | $1.2M | filing |
| 2026-04-29 | Patel Sanj K· CHAIRMAN & CEO | Option exercise | 22,544 | $30.93 | $697,285.92 | filing |
| 2026-04-28 | Patel Sanj K· CHAIRMAN & CEO | Sale | 243,596 | $52.02 | $12.7M | filing |
| 2026-04-28 | Patel Sanj K· CHAIRMAN & CEO | Sale | 113,673 | $51.47 | $5.9M | filing |
| 2026-04-28 | Patel Sanj K· CHAIRMAN & CEO | Option exercise | 431,904 | $10.36 | $4.5M | filing |
| 2026-04-28 | Patel Sanj K· CHAIRMAN & CEO | Sale | 74,635 | $50.43 | $3.8M | filing |
| 2026-04-28 | Patel Sanj K· CHAIRMAN & CEO | Sale | 51,750 | $54.02 | $2.8M | filing |
| 2026-04-28 | Patel Sanj K· CHAIRMAN & CEO | Option exercise | 51,750 | $30.93 | $1.6M | filing |
| 2026-04-28 | Quart Barry D | Sale | 13,099 | $50.10 | $656,259.90 | filing |
Showing the latest 25 transactions — full history in the linked SEC filings.
Fundamentals & filings from SEC EDGAR. Prices adjusted for splits & dividends. Not investment advice.