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Insmed Incorporated develops and commercializes therapies for patients with serious and rare diseases. The company offers ARIKAYCE for the treatment of Mycobacterium avium complex lung disease as part of a combination antibacterial drug regimen for adult patients. It is also developing Brensocatib, an oral reversible inhibitor of dipeptidyl peptidase 1.
Roles derived from SEC Form 4 filings.
Actuals from SEC filings; YoY vs the year-ago quarter. Analyst estimates & surprise require a data feed (coming soon).
| Line item | FY2020 | FY2021 | FY2022 | FY2023 | FY2024 | FY2025 |
|---|---|---|---|---|---|---|
| Revenue | $164.4M | $188.5M | $245.4M | $305.2M | $363.7M | $606.4M |
| Gross profit | — | — | — | — | — | — |
| Operating income | -$265.2M | -$375.1M | -$457.3M | -$709.6M | -$878.3M | -$1.2B |
| Net income | -$294.1M | -$434.7M | -$481.5M | -$749.6M | -$913.8M | -$1.3B |
| Diluted EPS | -$3.01 | -$3.88 | -$3.91 | -$5.34 | -$5.57 | -$6.42 |
| Operating cash flow | -$219.3M | -$363.3M | -$400.4M | -$536.2M | -$683.9M | -$935.0M |
| Free cash flow | -$225.6M | -$370.6M | -$410.3M | -$549.5M | -$705.8M | -$967.6M |
| Gross margin | — | — | — | — | — | — |
| Operating margin | -161.3% | -199.0% | -186.4% | -232.5% | -241.5% | -205.6% |
| Net margin | -178.9% | -230.6% | -196.3% | -245.6% | -251.2% | -210.5% |
| Line item | Q2 '24 | Q3 '24 | Q4 '24 | Q1 '25 | Q2 '25 | Q3 '25 | Q4 '25 | Q1 '26 |
|---|---|---|---|---|---|---|---|---|
| Revenue | $90.3M | $93.4M | $104.4M | $92.8M | $107.4M | $142.3M | $263.8M | $306.0M |
| Gross profit | — | — | — | — | — | — | — | — |
| Operating income | -$288.9M | -$213.4M | -$230.4M | -$248.1M | -$312.9M | -$366.0M | -$319.7M | -$153.3M |
| Net income | -$300.6M | -$220.5M | -$235.5M | -$256.6M | -$321.7M | -$370.0M | -$328.5M | -$163.6M |
| Diluted EPS | -$1.94 | -$1.27 | -$1.30 | -$1.42 | -$1.70 | -$1.75 | -$1.55 | -$0.76 |
| Operating cash flow | -$123.0M | -$180.9M | -$196.0M | -$262.1M | -$205.6M | -$219.8M | -$247.6M | -$222.7M |
| Free cash flow | -$129.7M | -$184.6M | -$202.8M | -$272.2M | -$209.1M | -$222.2M | -$264.2M | -$226.2M |
| Gross margin | — | — | — | — | — | — | — | — |
| Operating margin | -319.8% | -228.4% | -220.6% | -267.3% | -291.3% | -257.1% | -121.2% | -50.1% |
| Net margin | -332.8% | -236.0% | -225.5% | -276.4% | -299.5% | -260.0% | -124.5% | -53.5% |
Consensus revenue & EPS estimates and price targets will appear here once a forward-estimates data feed is connected.
| Date | Insider | Type | Shares | Price | Value | Filing |
|---|---|---|---|---|---|---|
| 2026-07-09 | Lewis William· Chair and CEO | Sale | 5,005 | $116.55 | $583,332.75 | filing |
| 2026-07-09 | Lewis William· Chair and CEO | Sale | 3,359 | $118.52 | $398,108.68 | filing |
| 2026-07-09 | Lewis William· Chair and CEO | Sale | 2,335 | $117.62 | $274,642.70 | filing |
| 2026-07-09 | Lewis William· Chair and CEO | Option exercise | 6,259 | $30.46 | $190,649.14 | filing |
| 2026-07-09 | Lewis William· Chair and CEO | Option exercise | 4,440 | $17.16 | $76,190.40 | filing |
| 2026-07-06 | Flammer Martina M.D.· Chief Medical Officer | Sale | 7,448 | $110.60 | $823,748.80 | filing |
| 2026-07-06 | Flammer Martina M.D.· Chief Medical Officer | Sale | 4,854 | $109.02 | $529,183.08 | filing |
| 2026-07-06 | Flammer Martina M.D.· Chief Medical Officer | Option exercise | 7,945 | $29.13 | $231,437.85 | filing |
| 2026-07-06 | Flammer Martina M.D.· Chief Medical Officer | Option exercise | 4,357 | $19.74 | $86,007.18 | filing |
| 2026-06-25 | Lewis William· Chair and CEO | Sale | 12,091 | $102.34 | $1.2M | filing |
| 2026-06-25 | Lewis William· Chair and CEO | Sale | 3,723 | $104.28 | $388,234.44 | filing |
| 2026-06-25 | Lewis William· Chair and CEO | Option exercise | 12,518 | $30.46 | $381,298.28 | filing |
| 2026-06-25 | Lewis William· Chair and CEO | Sale | 2,456 | $105.27 | $258,543.12 | filing |
| 2026-06-25 | Lewis William· Chair and CEO | Sale | 1,836 | $103.10 | $189,291.60 | filing |
| 2026-06-25 | Lewis William· Chair and CEO | Option exercise | 8,880 | $17.16 | $152,380.80 | filing |
| 2026-06-25 | Lewis William· Chair and CEO | Sale | 1,292 | $106.27 | $137,300.84 | filing |
| 2026-06-23 | Butera Samuele· SVP, GM, Global Respiratory | Award | 7,342 | — | — | filing |
| 2026-06-22 | Smith Michael Alexander· Chief Legal Officer | Sale | 1,806 | $95.82 | $173,050.92 | filing |
| 2026-06-08 | Lewis William· Chair and CEO | Sale | 6,515 | $94.03 | $612,605.45 | filing |
| 2026-06-05 | Flammer Martina M.D.· Chief Medical Officer | Sale | 1,858 | $103.78 | $192,823.24 | filing |
| 2026-06-03 | Lewis William· Chair and CEO | Sale | 7,605 | $102.27 | $777,763.35 | filing |
| 2026-06-03 | Flammer Martina M.D.· Chief Medical Officer | Sale | 2,566 | $102.27 | $262,424.82 | filing |
| 2026-06-03 | Bonstein Sara· Chief Financial Officer | Sale | 2,404 | $102.27 | $245,857.08 | filing |
| 2026-06-03 | Adsett Roger· Chief Operating Officer | Sale | 2,370 | $102.27 | $242,379.90 | filing |
| 2026-06-03 | Smith Michael Alexander· Chief Legal Officer | Sale | 2,159 | $102.27 | $220,800.93 | filing |
Showing the latest 25 transactions — full history in the linked SEC filings.
Fundamentals & filings from SEC EDGAR. Prices adjusted for splits & dividends. Not investment advice.