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Cytokinetics, Incorporated focuses on discovering, developing, and commercializing muscle activators and inhibitors as potential treatments for debilitating diseases. The company develops small molecule drug candidates primarily engineered to impact muscle function and contractility. Its drug candidates include omecamtiv mecarbil, a novel cardiac myosin activator that is in Phase III clinical trial in patients with heart failure.
Roles derived from SEC Form 4 filings.
Actuals from SEC filings; YoY vs the year-ago quarter. Analyst estimates & surprise require a data feed (coming soon).
| Line item | FY2020 | FY2021 | FY2022 | FY2023 | FY2024 | FY2025 |
|---|---|---|---|---|---|---|
| Revenue | $55.8M | $70.4M | $94.6M | $7.5M | $18.5M | $88.0M |
| Gross profit | — | — | — | — | — | — |
| Operating income | -$93.9M | -$186.3M | -$324.2M | -$496.2M | -$536.2M | -$612.3M |
| Net income | -$127.3M | -$215.3M | -$389.0M | -$526.2M | -$589.5M | -$785.0M |
| Diluted EPS | -$1.97 | -$2.80 | -$4.33 | -$5.45 | -$5.26 | -$6.54 |
| Operating cash flow | $8.9M | -$142.5M | -$299.5M | -$414.3M | -$395.9M | -$510.0M |
| Free cash flow | -$2.1M | -$191.4M | -$310.9M | -$415.7M | -$399.8M | -$534.8M |
| Gross margin | — | — | — | — | — | — |
| Operating margin | -168.3% | -264.5% | -342.8% | -6589.7% | -2902.7% | -695.4% |
| Net margin | -228.0% | -305.7% | -411.2% | -6988.6% | -3191.1% | -891.6% |
| Line item | Q2 '24 | Q3 '24 | Q4 '24 | Q1 '25 | Q2 '25 | Q3 '25 | Q4 '25 | Q1 '26 |
|---|---|---|---|---|---|---|---|---|
| Revenue | $249,000.00 | $463,000.00 | $16.9M | $1.6M | $66.8M | $1.9M | $17.8M | $19.4M |
| Gross profit | — | — | — | — | — | — | — | — |
| Operating income | -$130.2M | -$140.8M | -$139.0M | -$155.6M | -$111.5M | -$166.8M | -$178.4M | -$183.6M |
| Net income | -$143.3M | -$160.5M | -$150.0M | -$161.4M | -$134.4M | -$306.2M | -$183.0M | -$206.0M |
| Diluted EPS | -$1.31 | -$1.36 | -$1.26 | -$1.36 | -$1.12 | -$2.55 | -$1.51 | -$1.67 |
| Operating cash flow | -$99.3M | -$101.5M | -$65.6M | -$131.6M | -$128.2M | -$107.5M | -$142.7M | -$145.5M |
| Free cash flow | -$101.2M | -$102.2M | -$66.9M | -$137.3M | -$132.4M | -$116.9M | -$148.3M | -$151.4M |
| Gross margin | — | — | — | — | — | — | — | — |
| Operating margin | -52277.9% | -30410.6% | -821.4% | -9856.3% | -167.0% | -8613.4% | -1004.6% | -948.7% |
| Net margin | -57557.4% | -34674.9% | -886.3% | -10220.1% | -201.2% | -15815.0% | -1030.9% | -1064.5% |
Consensus revenue & EPS estimates and price targets will appear here once a forward-estimates data feed is connected.
| Date | Insider | Type | Shares | Price | Value | Filing |
|---|---|---|---|---|---|---|
| 2026-07-15 | HENDERSON JOHN T | Award | 272 | $82.62 | $22,472.64 | filing |
| 2026-07-15 | Kaye Edward M. MD | Award | 151 | $82.62 | $12,475.62 | filing |
| 2026-07-15 | Harrington Robert Arthur | Award | 151 | $82.62 | $12,475.62 | filing |
| 2026-07-15 | Daly James M | Award | 151 | $82.62 | $12,475.62 | filing |
| 2026-07-15 | WIERENGA WENDELL | Award | 75 | $82.62 | $6,196.50 | filing |
| 2026-07-15 | Wysenski Nancy | Award | 75 | $82.62 | $6,196.50 | filing |
| 2026-07-13 | Blum Robert I· President & CEO | Sale | 7,490 | $82.02 | $614,329.80 | filing |
| 2026-07-13 | Blum Robert I· President & CEO | Option exercise | 7,490 | $10.60 | $79,394.00 | filing |
| 2026-07-13 | Blum Robert I· President & CEO | Sale | 10 | $82.02 | $820.20 | filing |
| 2026-07-07 | Malik Fady Ibraham· EVP Research & Development | Sale | 3,500 | $86.62 | $303,170.00 | filing |
| 2026-07-07 | Malik Fady Ibraham· EVP Research & Development | Option exercise | 3,500 | $7.80 | $27,300.00 | filing |
| 2026-07-01 | Callos Andrew· EVP, Chief Commercial Officer | Sale | 15,000 | $85.80 | $1.3M | filing |
| 2026-07-01 | Blum Robert I· President & CEO | Sale | 7,500 | $84.92 | $636,900.00 | filing |
| 2026-07-01 | Callos Andrew· EVP, Chief Commercial Officer | Option exercise | 15,000 | $23.26 | $348,900.00 | filing |
| 2026-07-01 | Lee Sung· EVP, Chief Financial Officer | Sale | 1,112 | $87.79 | $97,622.48 | filing |
| 2026-07-01 | Lee Sung· EVP, Chief Financial Officer | Option exercise | 1,112 | $48.51 | $53,943.12 | filing |
| 2026-06-29 | Lee Sung· EVP, Chief Financial Officer | Sale | 3,134 | $85.00 | $266,390.00 | filing |
| 2026-06-29 | Lee Sung· EVP, Chief Financial Officer | Option exercise | 1,113 | $48.51 | $53,991.63 | filing |
| 2026-06-29 | Lee Sung· EVP, Chief Financial Officer | Option exercise | 823 | $44.36 | $36,508.28 | filing |
| 2026-06-29 | Lee Sung· EVP, Chief Financial Officer | Option exercise | 822 | $44.36 | $36,463.92 | filing |
| 2026-06-29 | Lee Sung· EVP, Chief Financial Officer | Option exercise | 188 | $44.36 | $8,339.68 | filing |
| 2026-06-29 | Lee Sung· EVP, Chief Financial Officer | Option exercise | 188 | $44.36 | $8,339.68 | filing |
| 2026-06-24 | Lee Sung· EVP, Chief Financial Officer | Sale | 38,730 | $82.30 | $3.2M | filing |
| 2026-06-24 | Lee Sung· EVP, Chief Financial Officer | Option exercise | 23,370 | $48.51 | $1.1M | filing |
| 2026-06-24 | Lee Sung· EVP, Chief Financial Officer | Option exercise | 9,307 | $44.36 | $412,858.52 | filing |
Showing the latest 25 transactions — full history in the linked SEC filings.
Fundamentals & filings from SEC EDGAR. Prices adjusted for splits & dividends. Not investment advice.