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Cue Biopharma, Inc. develops biologic drugs for the selective modulation of the human immune system to treat a range of cancers, chronic infectious diseases, and autoimmune disorders. Its lead drug candidate is CUE-101, a fusion protein biologic that is in Phase 1b clinical trial designed to target and activate antigen-specific T cells for human papilloma virus-driven cancers.
Roles derived from SEC Form 4 filings.
Actuals from SEC filings; YoY vs the year-ago quarter. Analyst estimates & surprise require a data feed (coming soon).
| Line item | FY2020 | FY2021 | FY2022 | FY2023 | FY2024 | FY2025 |
|---|---|---|---|---|---|---|
| Revenue | $3.2M | $14.9M | $1.2M | $5.5M | $9.3M | $27.5M |
| Gross profit | — | — | — | — | — | — |
| Operating income | -$45.0M | -$43.7M | -$53.2M | -$52.1M | -$41.5M | -$26.6M |
| Net income | -$44.8M | -$44.2M | -$53.0M | -$50.7M | -$40.7M | -$26.6M |
| Diluted EPS | — | -$1.41 | -$1.49 | -$1.11 | -$0.72 | -$0.28 |
| Operating cash flow | -$32.5M | -$38.8M | -$41.8M | -$40.0M | -$36.3M | -$21.7M |
| Free cash flow | -$33.1M | -$39.8M | -$42.0M | -$40.0M | -$36.4M | -$21.9M |
| Gross margin | — | — | — | — | — | — |
| Operating margin | -1428.0% | -292.6% | -4275.1% | -949.9% | -446.9% | -96.7% |
| Net margin | -1419.8% | -295.6% | -4257.8% | -924.1% | -438.0% | -96.9% |
| Line item | Q2 '24 | Q3 '24 | Q4 '24 | Q1 '25 | Q2 '25 | Q3 '25 | Q4 '25 | Q1 '26 |
|---|---|---|---|---|---|---|---|---|
| Revenue | $2.7M | $3.3M | $1.6M | $421,000.00 | $3.0M | $2.1M | $21.9M | $5.7M |
| Gross profit | — | — | — | — | — | — | — | — |
| Operating income | -$10.4M | -$8.8M | -$9.6M | -$12.3M | -$8.6M | -$7.6M | $2.0M | -$5.4M |
| Net income | -$10.2M | -$8.7M | -$9.5M | -$12.3M | -$8.5M | -$7.4M | $1.6M | -$5.2M |
| Diluted EPS | -$0.20 | -$0.17 | -$0.10 | -$4.95 | -$0.09 | -$0.07 | $4.83 | -$1.08 |
| Operating cash flow | -$10.0M | -$7.5M | -$9.0M | -$8.2M | -$3.4M | -$9.0M | -$1.1M | -$10.9M |
| Free cash flow | -$10.0M | -$7.5M | -$9.0M | -$8.3M | -$3.4M | -$9.0M | -$1.1M | -$11.1M |
| Gross margin | — | — | — | — | — | — | — | — |
| Operating margin | -390.6% | -264.2% | -611.3% | -2921.4% | -292.3% | -353.4% | 9.0% | -94.1% |
| Net margin | -382.7% | -259.6% | -602.5% | -2911.4% | -287.1% | -346.6% | 7.2% | -91.1% |
Consensus revenue & EPS estimates and price targets will appear here once a forward-estimates data feed is connected.
| Date | Insider | Type | Shares | Price | Value | Filing |
|---|---|---|---|---|---|---|
| 2026-07-13 | Borie Dominique Christian· Chief Medical Officer | Award | 31,500 | $0.00 | $0.00 | filing |
| 2026-07-09 | Garzone Pamela | Award | 21,800 | $0.00 | $0.00 | filing |
| 2026-07-09 | Camardo Daniel A. | Award | 21,800 | $0.00 | $0.00 | filing |
| 2026-07-09 | Sarraf Pasha | Award | 21,800 | $0.00 | $0.00 | filing |
| 2026-07-09 | Meehan Viola Mong | Award | 21,800 | $0.00 | $0.00 | filing |
| 2026-07-09 | Meluzio Michael Vincent· VP, Prin. Accounting Officer | Award | 40,942 | $0.00 | $0.00 | filing |
| 2026-07-09 | Ray Sumita· Chief Legal Compliance Officer | Award | 54,589 | $0.00 | $0.00 | filing |
| 2026-07-09 | Lin Shao-Lee· Chief Executive Officer | Award | 327,537 | $0.00 | $0.00 | filing |
| 2026-05-03 | Lin Shao-Lee· CHIEF EXECUTIVE OFFICER | Award | 327,537 | $0.00 | $0.00 | filing |
| 2025-12-30 | Sarraf Pasha | Buy | 86,947 | $0.32 | $27,596.98 | filing |
| 2025-12-30 | Sarraf Pasha | Buy | 78,116 | $0.31 | $24,325.32 | filing |
| 2025-12-30 | Sarraf Pasha | Buy | 77,417 | $0.30 | $23,348.97 | filing |
| 2025-12-30 | Sarraf Pasha | Buy | 77,148 | $0.30 | $23,167.54 | filing |
| 2025-12-30 | Sarraf Pasha | Buy | 4,229 | $0.31 | $1,308.45 | filing |
Latest 14 transactions.
Fundamentals & filings from SEC EDGAR. Prices adjusted for splits & dividends. Not investment advice.