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Codexis, Inc. discovers, develops, and sells enzymes and other proteins. The company also provides biocatalyst screening and protein engineering services. It sells its products to pharmaceutical manufacturers through its direct sales and business development force in the United States and Europe.
Roles derived from SEC Form 4 filings.
Actuals from SEC filings; YoY vs the year-ago quarter. Analyst estimates & surprise require a data feed (coming soon).
| Line item | FY2020 | FY2021 | FY2022 | FY2023 | FY2024 | FY2025 |
|---|---|---|---|---|---|---|
| Revenue | $69.1M | $104.8M | $138.6M | $70.1M | $59.3M | $70.4M |
| Gross profit | — | — | — | — | — | — |
| Operating income | -$23.9M | -$22.7M | -$34.9M | -$68.1M | -$58.5M | -$41.7M |
| Net income | -$24.0M | -$21.3M | -$33.6M | -$76.2M | -$65.3M | -$44.0M |
| Diluted EPS | -$0.40 | -$0.33 | -$0.51 | -$1.12 | -$0.89 | -$0.50 |
| Operating cash flow | -$16.5M | -$14.3M | $11.3M | -$52.6M | -$49.4M | -$19.4M |
| Free cash flow | -$20.2M | -$28.1M | $3.0M | -$57.1M | -$53.7M | -$23.8M |
| Gross margin | — | — | — | — | — | — |
| Operating margin | -34.6% | -21.7% | -25.2% | -97.0% | -98.6% | -59.3% |
| Net margin | -34.8% | -20.3% | -24.2% | -108.7% | -110.0% | -62.5% |
| Line item | Q2 '24 | Q3 '24 | Q4 '24 | Q1 '25 | Q2 '25 | Q3 '25 | Q4 '25 | Q1 '26 |
|---|---|---|---|---|---|---|---|---|
| Revenue | $8.0M | $12.8M | $21.5M | $7.5M | $15.3M | $8.6M | $38.9M | $15.2M |
| Gross profit | — | — | — | — | — | — | — | — |
| Operating income | -$22.7M | -$16.6M | -$7.3M | -$20.5M | -$12.9M | -$18.9M | $10.6M | -$8.0M |
| Net income | -$22.8M | -$20.6M | -$10.4M | -$20.7M | -$13.3M | -$19.6M | $9.6M | -$8.7M |
| Diluted EPS | -$0.32 | -$0.29 | -$0.12 | -$0.25 | -$0.16 | -$0.22 | $0.13 | -$0.10 |
| Operating cash flow | -$12.2M | -$13.0M | -$16.5M | -$13.8M | -$18.0M | -$7.7M | $20.1M | -$13.2M |
| Free cash flow | -$12.6M | -$14.0M | -$18.2M | -$15.1M | -$20.5M | -$7.9M | $19.6M | -$13.3M |
| Gross margin | — | — | — | — | — | — | — | — |
| Operating margin | -284.9% | -129.0% | -34.2% | -271.6% | -83.9% | -220.3% | 27.1% | -52.7% |
| Net margin | -285.2% | -160.8% | -48.4% | -274.3% | -86.6% | -228.1% | 24.7% | -57.1% |
Consensus revenue & EPS estimates and price targets will appear here once a forward-estimates data feed is connected.
| Date | Insider | Type | Shares | Price | Value | Filing |
|---|---|---|---|---|---|---|
| 2026-06-11 | De Vre Raymond | Sale | 2,605 | $2.37 | $6,173.85 | filing |
| 2026-02-24 | Lutz Stefan· Chief Scientific Officer | Sale | 5,862 | $1.13 | $6,641.06 | filing |
| 2026-02-06 | MOORE ALISON· President and CEO | Sale | 3,826 | $1.31 | $5,000.96 | filing |
| 2026-02-06 | Erbez Georgia· See Remarks | Sale | 3,826 | $1.31 | $5,000.96 | filing |
| 2026-02-06 | Lutz Stefan· Chief Scientific Officer | Sale | 2,492 | $1.31 | $3,257.29 | filing |
| 2026-01-07 | Lutz Stefan· CSO | Sale | 4,685 | $1.70 | $7,949.51 | filing |
| 2025-12-01 | Opaleye Management Inc. | Sale | 245,000 | $1.67 | $408,537.50 | filing |
| 2025-12-01 | Opaleye Management Inc. | Sale | 245,000 | $1.67 | $408,537.50 | filing |
| 2025-12-01 | Opaleye Management Inc. | Sale | 8,533 | $1.67 | $14,228.78 | filing |
| 2025-12-01 | Opaleye Management Inc. | Sale | 8,533 | $1.67 | $14,228.78 | filing |
| 2025-11-28 | Opaleye Management Inc. | Sale | 105,000 | $1.75 | $183,750.00 | filing |
| 2025-11-28 | Opaleye Management Inc. | Sale | 105,000 | $1.75 | $183,750.00 | filing |
| 2025-11-28 | Opaleye Management Inc. | Sale | 2,490 | $1.75 | $4,357.50 | filing |
| 2025-11-28 | Opaleye Management Inc. | Sale | 2,490 | $1.75 | $4,357.50 | filing |
| 2025-11-26 | Opaleye Management Inc. | Sale | 148,318 | $1.74 | $258,266.13 | filing |
| 2025-11-26 | Opaleye Management Inc. | Sale | 148,318 | $1.74 | $258,266.13 | filing |
| 2025-11-26 | Opaleye Management Inc. | Sale | 5,000 | $1.74 | $8,706.50 | filing |
| 2025-11-26 | Opaleye Management Inc. | Sale | 5,000 | $1.74 | $8,706.50 | filing |
| 2025-11-21 | WOLF DENNIS P | Sale | 8,952 | $1.56 | $13,988.40 | filing |
| 2025-11-13 | MOORE ALISON· President and CEO | Award | 85,000 | $0.00 | $0.00 | filing |
| 2025-11-12 | Opaleye Management Inc. | Sale | 890,000 | $1.94 | $1.7M | filing |
| 2025-11-12 | Opaleye Management Inc. | Sale | 165,000 | $1.96 | $323,730.00 | filing |
| 2025-11-12 | Opaleye Management Inc. | Sale | 27,459 | $1.94 | $53,193.57 | filing |
| 2025-11-11 | Opaleye Management Inc. | Sale | 535,000 | $1.80 | $962,679.00 | filing |
| 2025-11-11 | Opaleye Management Inc. | Sale | 535,000 | $1.80 | $962,679.00 | filing |
Showing the latest 25 transactions — full history in the linked SEC filings.
Fundamentals & filings from SEC EDGAR. Prices adjusted for splits & dividends. Not investment advice.