BICYCLE THERAPEUTICS PLC
BCYCNasdaq
$4.21
↑ +0.7%Jul 17 close · end-of-day
Price
1Y↓ -45.9%
End-of-day closes; the latest point is the live 15-min-delayed price · split & dividend adjusted · chart by TradingView
Key statistics
Market Cap
$293.4M
Enterprise Value
-$266.1M
P/E
—
P/S
4.6
P/B
0.5
EV/EBITDA
—
PEG
—
FCF Yield
-79.0%
Dividend Yield
0.0%
Revenue (TTM)
$63.5M
Net Income (TTM)
-$219.0M
Free Cash Flow (TTM)
-$231.7M
Gross Margin
—
Operating Margin
-381.7%
Net Margin
-344.9%
ROE
-39.5%
ROIC
—
Debt / Equity
—
Net Cash
$559.5M
Return 1Y
-47.6%
Company profile
Bicycle Therapeutics plc develops a class of medicines for diseases that are underserved by existing therapeutics. Its lead product candidate is BT1718, a bicycle toxin conjugate (BTC), which is in Phase I/IIa clinical trials targeting tumors that express Membrane Type 1 matrix metalloprotease. The company is developing THR-149, a plasma kallikrein inhibitor that completed Phase II clinical trials for the treatment of diabetic macular edema. BT7480, a Bicycle tumor-targeted immune cell agonist (TICA) targeting Nectin-4 and agonizing; BT
- CEO
- Kevin Lee
- Sector
- Manufacturing
- Industry
- Pharmaceutical Products
- Employees
- 240
- Website
- bicycletherapeutics.com
Management & directors
- Hannay Michael Charles FergusonCHIEF PROD & SUPPLY CHAIN OFF
- Lee KevinCHIEF EXECUTIVE OFFICER
- Perry Jennifer ScottChief Operating Officer
- Skynner MichaelCHIEF SCIENTIFIC OFFICER
- Thompson Travis AlvinCHIEF ACCOUNTING OFFICER
- Milnes AlistairCHIEF OPERATING OFFICER
- Young AlethiaChief Financial Officer
Roles derived from SEC Form 4 filings.
Earnings
BCYC Q1 2026 Earnings
Period ends 2026-03-31
MetricActualYoY
Revenue$887,000.00↓ -91.1%
Diluted EPS-$0.87↓ -1.1%
Actuals from SEC filings; YoY vs the year-ago quarter. Analyst estimates & surprise require a data feed (coming soon).
Financial statements
| Line item | FY2020 | FY2021 | FY2022 | FY2023 | FY2024 | FY2025 |
|---|---|---|---|---|---|---|
| Revenue | $10.4M | $11.7M | $14.5M | $27.0M | $35.3M | $72.6M |
| Gross profit | — | — | — | — | — | — |
| Operating income | -$52.0M | -$65.6M | -$116.7M | -$189.9M | -$209.9M | -$247.1M |
| Net income | -$51.0M | -$66.8M | -$112.7M | -$180.7M | -$169.0M | -$219.0M |
| Diluted EPS | -$2.66 | -$2.67 | -$3.80 | -$5.08 | -$2.90 | -$3.16 |
| Operating cash flow | -$17.8M | -$14.8M | -$86.1M | -$60.6M | -$164.7M | -$249.7M |
| Free cash flow | -$19.0M | -$16.8M | -$105.1M | -$63.6M | -$166.0M | -$252.0M |
| Gross margin | — | — | — | — | — | — |
| Operating margin | -500.1% | -561.0% | -806.6% | -704.1% | -595.0% | -340.4% |
| Net margin | -491.0% | -571.2% | -779.3% | -669.7% | -479.2% | -301.7% |
| Line item | Q2 '24 | Q3 '24 | Q4 '24 | Q1 '25 | Q2 '25 | Q3 '25 | Q4 '25 | Q1 '26 |
|---|---|---|---|---|---|---|---|---|
| Revenue | $9.4M | $2.7M | $3.7M | $10.0M | $2.9M | $11.7M | $48.0M | $887,000.00 |
| Gross profit | — | — | — | — | — | — | — | — |
| Operating income | -$46.6M | -$63.8M | -$67.7M | -$70.2M | -$86.6M | -$65.6M | -$24.7M | -$65.5M |
| Net income | -$39.8M | -$50.8M | -$51.9M | -$60.8M | -$79.0M | -$59.1M | -$20.2M | -$60.8M |
| Diluted EPS | -$0.77 | -$0.74 | -$0.77 | -$0.88 | -$1.14 | -$0.85 | -$0.29 | -$0.87 |
| Operating cash flow | -$44.6M | -$39.8M | -$9.4M | -$86.4M | -$72.8M | -$71.2M | -$19.3M | -$65.9M |
| Free cash flow | -$45.0M | -$40.3M | -$9.8M | -$87.0M | -$73.3M | -$71.8M | -$19.9M | -$66.6M |
| Gross margin | — | — | — | — | — | — | — | — |
| Operating margin | -498.3% | -2385.9% | -1824.8% | -703.7% | -2965.8% | -558.6% | -51.5% | -7382.4% |
| Net margin | -425.3% | -1898.4% | -1398.4% | -608.9% | -2703.8% | -503.7% | -42.0% | -6857.4% |
Company news
Jul 3, 2026
Analyst estimates
Coming soonConsensus revenue & EPS estimates and price targets will appear here once a forward-estimates data feed is connected.
Insider transactions
BoughtSoldMonthly insider $ volume · trailing 12 months
| Date | Insider | Type | Shares | Price | Value | Filing |
|---|---|---|---|---|---|---|
| 2026-07-06 | Lee Kevin· CHIEF EXECUTIVE OFFICER | Sale | 1,737 | $4.31 | $7,486.47 | filing |
| 2026-07-06 | Skynner Michael· CHIEF SCIENTIFIC OFFICER | Sale | 532 | $4.31 | $2,292.92 | filing |
| 2026-07-06 | Perry Jennifer Scott· Chief Operating Officer | Sale | 333 | $4.34 | $1,445.22 | filing |
| 2026-07-06 | Hannay Michael Charles Ferguson· CHIEF PROD & SUPPLY CHAIN OFF | Sale | 255 | $4.31 | $1,099.05 | filing |
| 2026-07-06 | Thompson Travis Alvin· Chief Financial Officer | Sale | 104 | $4.31 | $448.24 | filing |
| 2026-07-06 | Perry Jennifer Scott· Chief Operating Officer | Sale | 43 | $4.31 | $185.33 | filing |
| 2026-07-02 | Lee Kevin· CHIEF EXECUTIVE OFFICER | Sale | 5,905 | $4.27 | $25,214.35 | filing |
| 2026-07-02 | Skynner Michael· CHIEF SCIENTIFIC OFFICER | Sale | 1,859 | $4.27 | $7,937.93 | filing |
| 2026-07-02 | Hannay Michael Charles Ferguson· CHIEF PROD & SUPPLY CHAIN OFF | Sale | 1,506 | $4.27 | $6,430.62 | filing |
| 2026-07-02 | Perry Jennifer Scott· Chief Operating Officer | Sale | 1,036 | $4.27 | $4,423.72 | filing |
| 2026-07-02 | Thompson Travis Alvin· Chief Financial Officer | Sale | 819 | $4.27 | $3,497.13 | filing |
| 2026-04-06 | Lee Kevin· CHIEF EXECUTIVE OFFICER | Sale | 1,716 | $5.05 | $8,665.80 | filing |
| 2026-04-06 | Skynner Michael· CHIEF SCIENTIFIC OFFICER | Sale | 525 | $5.05 | $2,651.25 | filing |
| 2026-04-06 | Perry Jennifer Scott· Chief Operating Officer | Sale | 333 | $5.04 | $1,678.32 | filing |
| 2026-04-06 | Hannay Michael Charles Ferguson· CHIEF PROD & SUPPLY CHAIN OFF | Sale | 251 | $5.05 | $1,267.55 | filing |
| 2026-04-06 | Thompson Travis Alvin· Chief Financial Officer | Sale | 102 | $5.05 | $515.10 | filing |
| 2026-04-06 | Perry Jennifer Scott· Chief Operating Officer | Sale | 37 | $5.05 | $186.85 | filing |
| 2026-04-02 | Lee Kevin· CHIEF EXECUTIVE OFFICER | Sale | 5,967 | $4.91 | $29,297.97 | filing |
| 2026-04-02 | Skynner Michael· CHIEF SCIENTIFIC OFFICER | Sale | 1,879 | $4.91 | $9,225.89 | filing |
| 2026-04-02 | Hannay Michael Charles Ferguson· CHIEF PROD & SUPPLY CHAIN OFF | Sale | 1,521 | $4.91 | $7,468.11 | filing |
| 2026-04-02 | Perry Jennifer Scott· Chief Operating Officer | Sale | 1,038 | $4.91 | $5,096.58 | filing |
| 2026-04-02 | Thompson Travis Alvin· Chief Financial Officer | Sale | 799 | $4.91 | $3,923.09 | filing |
| 2026-01-05 | Lee Kevin· CHIEF EXECUTIVE OFFICER | Sale | 10,989 | $6.46 | $70,988.94 | filing |
| 2026-01-05 | Milnes Alistair· CHIEF OPERATING OFFICER | Sale | 3,416 | $6.46 | $22,067.36 | filing |
| 2026-01-05 | Skynner Michael· CHIEF TECHNOLOGY OFFICER | Sale | 3,266 | $6.46 | $21,098.36 | filing |
Showing the latest 25 transactions — full history in the linked SEC filings.
Fundamentals & filings from SEC EDGAR. Prices adjusted for splits & dividends. Not investment advice.