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aTyr Pharma, Inc. engages in the discovery and development of medicines based on novel immunological pathways in the United States. The company's lead therapeutic candidate is efzofitimod, a selective modulator of NRP2 that is in Phase II clinical trial for pulmonary sarcoidosis; and in Phase 1b/2a clinical trials for treatment of other interstitial lung diseases (ILDs) The company was incorporated in 2005 and is headquartered in San Diego, California.
Roles derived from SEC Form 4 filings.
Actuals from SEC filings; YoY vs the year-ago quarter. Analyst estimates & surprise require a data feed (coming soon).
| Line item | FY2020 | FY2021 | FY2022 | FY2023 | FY2024 | FY2025 |
|---|---|---|---|---|---|---|
| Revenue | $10.5M | $0.00 | $10.4M | $353,000.00 | $235,000.00 | $190,000.00 |
| Gross profit | — | — | — | — | — | — |
| Operating income | -$15.9M | -$34.0M | -$46.4M | -$54.9M | -$67.9M | -$77.6M |
| Net income | -$16.2M | -$33.8M | -$45.3M | -$50.4M | -$64.0M | -$74.1M |
| Diluted EPS | -$1.77 | -$1.77 | -$1.60 | -$0.94 | -$0.86 | -$0.80 |
| Operating cash flow | -$15.3M | -$33.1M | -$41.9M | -$33.2M | -$69.1M | -$62.0M |
| Free cash flow | -$15.5M | -$33.3M | -$43.5M | -$37.4M | -$69.2M | -$62.1M |
| Gross margin | — | — | — | — | — | — |
| Operating margin | -152.2% | — | -446.8% | -15557.8% | -28899.6% | -40856.3% |
| Net margin | -155.2% | — | -436.5% | -14274.5% | -27243.8% | -39009.5% |
| Line item | Q2 '24 | Q3 '24 | Q4 '24 | Q1 '25 | Q2 '25 | Q3 '25 | Q4 '25 | Q1 '26 |
|---|---|---|---|---|---|---|---|---|
| Revenue | $0.00 | $0.00 | $0.00 | $0.00 | $0.00 | $190,000.00 | $0.00 | — |
| Gross profit | — | — | — | — | — | — | — | — |
| Operating income | -$17.3M | -$18.1M | -$15.8M | -$15.8M | -$20.3M | -$26.7M | -$14.8M | -$11.4M |
| Net income | -$16.3M | -$17.3M | -$15.0M | -$14.9M | -$19.5M | -$25.7M | -$14.0M | -$10.8M |
| Diluted EPS | -$0.23 | -$0.23 | -$0.17 | -$0.17 | -$0.22 | -$0.26 | -$0.15 | -$0.11 |
| Operating cash flow | -$20.4M | -$13.2M | -$13.1M | -$15.4M | -$13.9M | -$20.5M | -$12.2M | -$12.5M |
| Free cash flow | -$20.5M | -$13.2M | -$13.2M | -$15.4M | -$13.9M | -$20.5M | -$12.2M | -$12.7M |
| Gross margin | — | — | — | — | — | — | — | — |
| Operating margin | — | — | — | — | — | -14076.3% | — | — |
| Net margin | — | — | — | — | — | -13549.5% | — | — |
Consensus revenue & EPS estimates and price targets will appear here once a forward-estimates data feed is connected.
| Date | Insider | Type | Shares | Price | Value | Filing |
|---|---|---|---|---|---|---|
| 2026-05-27 | SCHIMMEL PAUL | Buy | 100,000 | $0.50 | $49,630.00 | filing |
| 2026-02-04 | Shukla Sanjay· President and CEO | Sale | 3,745 | $0.98 | $3,655.12 | filing |
| 2026-02-04 | Broadfoot Jill Marie· Chief Financial Officer | Sale | 1,558 | $0.98 | $1,520.61 | filing |
| 2026-02-04 | Krueger Nancy· General Counsel | Sale | 1,118 | $0.98 | $1,091.28 | filing |
| 2026-02-03 | Shukla Sanjay· President and CEO | Option exercise | 10,375 | — | — | filing |
| 2026-02-03 | Broadfoot Jill Marie· Chief Financial Officer | Option exercise | 3,750 | — | — | filing |
| 2026-02-03 | Krueger Nancy· General Counsel | Option exercise | 2,687 | — | — | filing |
| 2025-10-09 | SCHIMMEL PAUL | Buy | 317,999 | $0.94 | $299,364.26 | filing |
| 2025-10-08 | SCHIMMEL PAUL | Buy | 682,001 | $0.90 | $612,436.90 | filing |
Latest 9 transactions.
Fundamentals & filings from SEC EDGAR. Prices adjusted for splits & dividends. Not investment advice.