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AnaptysBio, Inc. engages in developing therapeutic product candidates for inflammation and immuno-oncology indications. Its products include Imsidolimab, an antibody that inhibits the interleukin-36 receptor (IL-36R) for the treatment of various dermatological inflammatory diseases. The company also focuses on developing various antibody programs that are advanced to preclinical and clinical milestones under its collaborations.
Roles derived from SEC Form 4 filings.
Actuals from SEC filings; YoY vs the year-ago quarter. Analyst estimates & surprise require a data feed (coming soon).
| Line item | FY2020 | FY2021 | FY2022 | FY2023 | FY2024 | FY2025 |
|---|---|---|---|---|---|---|
| Revenue | $75.0M | $63.2M | $10.3M | $17.2M | $91.3M | $234.6M |
| Gross profit | — | — | — | — | — | — |
| Operating income | -$23.9M | -$56.8M | -$115.2M | -$164.4M | -$114.9M | $47.9M |
| Net income | -$19.9M | -$57.8M | -$128.7M | -$163.6M | -$145.2M | -$13.2M |
| Diluted EPS | -$0.73 | -$2.11 | -$4.57 | -$6.08 | -$5.12 | -$0.46 |
| Operating cash flow | -$14.2M | -$45.9M | -$73.6M | -$120.8M | -$135.3M | $19.7M |
| Free cash flow | -$14.7M | -$47.3M | -$74.0M | -$121.6M | -$135.7M | $19.6M |
| Gross margin | — | — | — | — | — | — |
| Operating margin | -31.8% | -89.9% | -1119.4% | -958.3% | -125.9% | 20.4% |
| Net margin | -26.6% | -91.5% | -1251.3% | -953.7% | -159.1% | -5.6% |
| Line item | Q2 '24 | Q3 '24 | Q4 '24 | Q1 '25 | Q2 '25 | Q3 '25 | Q4 '25 | Q1 '26 |
|---|---|---|---|---|---|---|---|---|
| Revenue | $11.0M | $30.0M | $43.1M | $27.8M | $22.3M | $76.3M | $108.2M | $25.6M |
| Gross profit | — | — | — | — | — | — | — | — |
| Operating income | -$40.3M | -$22.8M | -$9.7M | -$27.5M | -$26.2M | $34.7M | $66.9M | -$34.6M |
| Net income | -$46.7M | -$32.9M | -$21.8M | -$39.3M | -$38.6M | $15.1M | $49.6M | -$52.9M |
| Diluted EPS | -$1.71 | -$1.14 | -$0.63 | -$1.28 | -$1.34 | $0.52 | $1.64 | -$1.84 |
| Operating cash flow | -$21.3M | -$10.1M | -$66.7M | -$10.7M | -$40.2M | -$27.4M | $98.0M | -$25.9M |
| Free cash flow | -$21.4M | -$10.1M | -$66.9M | -$10.7M | -$40.3M | -$27.4M | $98.0M | -$25.9M |
| Gross margin | — | — | — | — | — | — | — | — |
| Operating margin | -367.5% | -75.8% | -22.4% | -99.2% | -117.5% | 45.5% | 61.8% | -135.5% |
| Net margin | -425.3% | -109.4% | -50.5% | -141.6% | -173.5% | 19.8% | 45.8% | -206.9% |
Consensus revenue & EPS estimates and price targets will appear here once a forward-estimates data feed is connected.
| Date | Insider | Type | Shares | Price | Value | Filing |
|---|---|---|---|---|---|---|
| 2026-06-15 | Schmid John P. | Option exercise | 6,030 | $0.00 | $0.00 | filing |
| 2026-06-15 | RENTON HOLLINGS | Option exercise | 6,030 | $0.00 | $0.00 | filing |
| 2026-06-15 | Orwin John A | Option exercise | 6,030 | $0.00 | $0.00 | filing |
| 2026-04-20 | ANAPTYSBIO, INC | J | 100 | — | — | filing |
| 2026-03-30 | Schmid John P. | Sale | 12,596 | $55.71 | $701,706.79 | filing |
| 2026-03-30 | Schmid John P. | Sale | 7,527 | $56.70 | $426,782.41 | filing |
| 2026-03-30 | Schmid John P. | Sale | 522 | $57.40 | $29,962.23 | filing |
| 2026-03-27 | Faga Daniel· President, CEO | Sale | 3,662 | $58.62 | $214,651.06 | filing |
| 2026-03-27 | Faga Daniel· President, CEO | Sale | 3,155 | $64.19 | $202,522.29 | filing |
| 2026-03-27 | Faga Daniel· President, CEO | Sale | 3,038 | $65.20 | $198,072.13 | filing |
| 2026-03-27 | Faga Daniel· President, CEO | Sale | 2,592 | $63.35 | $164,203.98 | filing |
| 2026-03-27 | Faga Daniel· President, CEO | Sale | 2,570 | $57.91 | $148,819.19 | filing |
| 2026-03-27 | Faga Daniel· President, CEO | Sale | 1,012 | $62.15 | $62,898.33 | filing |
| 2026-03-27 | Faga Daniel· President, CEO | Sale | 550 | $60.63 | $33,344.52 | filing |
| 2026-03-27 | Faga Daniel· President, CEO | Sale | 490 | $59.62 | $29,215.61 | filing |
| 2026-03-27 | Faga Daniel· President, CEO | Sale | 510 | $56.61 | $28,872.63 | filing |
| 2026-03-27 | Faga Daniel· President, CEO | Sale | 100 | $65.99 | $6,599.00 | filing |
| 2026-03-25 | Faga Daniel· President, CEO | Award | 34,300 | — | — | filing |
| 2026-02-11 | LOUMEAU ERIC J· CHIEF LEGAL OFFICER | Sale | 10,000 | $54.00 | $540,000.00 | filing |
| 2026-02-11 | LOUMEAU ERIC J· CHIEF LEGAL OFFICER | Option exercise | 10,000 | $29.70 | $297,000.00 | filing |
| 2026-01-15 | Marquet Magda | Sale | 9,290 | $48.12 | $446,999.50 | filing |
| 2026-01-15 | Marquet Magda | Option exercise | 11,000 | $26.11 | $287,210.00 | filing |
| 2026-01-15 | Marquet Magda | Sale | 1,710 | $48.85 | $83,531.79 | filing |
| 2026-01-08 | Faga Daniel· President, CEO | Sale | 14,281 | $44.71 | $638,503.51 | filing |
| 2026-01-08 | Lizzul Paul F.· Chief Medical Officer | Sale | 3,650 | $44.71 | $163,191.50 | filing |
Showing the latest 25 transactions — full history in the linked SEC filings.
Fundamentals & filings from SEC EDGAR. Prices adjusted for splits & dividends. Not investment advice.