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We are a clinical stage biopharmaceutical company developing precision oncology medicines that we match to patients whose tumors are predicted to be sensitive to each specific medicine by utilizing our proprietary proteomics-based patient responder identification platform. We were incorporated under the laws of the State of Delaware in March 2018. Our principal executive offices are located at 480 Arsenal Way, Suite 100, Watertown, Massachusetts.
Roles derived from SEC Form 4 filings.
Actuals from SEC filings; YoY vs the year-ago quarter. Analyst estimates & surprise require a data feed (coming soon).
| Line item | FY2021 | FY2022 | FY2023 | FY2024 | FY2025 |
|---|---|---|---|---|---|
| Revenue | — | — | — | — | — |
| Gross profit | — | — | — | — | — |
| Operating income | -$16.2M | -$32.7M | -$67.1M | -$89.2M | -$84.1M |
| Net income | -$16.2M | -$31.2M | -$60.4M | -$80.6M | -$77.9M |
| Diluted EPS | -$9.32 | -$7.56 | -$2.74 | -$2.38 | -$2.02 |
| Operating cash flow | -$14.0M | -$30.1M | -$42.6M | -$65.7M | -$63.7M |
| Free cash flow | -$14.2M | -$32.3M | -$43.9M | -$68.4M | -$65.3M |
| Gross margin | — | — | — | — | — |
| Operating margin | — | — | — | — | — |
| Net margin | — | — | — | — | — |
| Line item | Q2 '24 | Q3 '24 | Q4 '24 | Q1 '25 | Q2 '25 | Q3 '25 | Q4 '25 | Q1 '26 |
|---|---|---|---|---|---|---|---|---|
| Revenue | — | — | — | — | — | — | — | — |
| Gross profit | — | — | — | — | — | — | — | — |
| Operating income | -$21.4M | -$25.1M | -$25.0M | -$21.7M | -$22.6M | -$19.7M | -$20.1M | -$19.9M |
| Net income | -$18.8M | -$22.4M | -$22.8M | -$19.7M | -$21.0M | -$18.2M | -$19.0M | -$19.0M |
| Diluted EPS | -$0.52 | -$0.59 | -$0.54 | -$0.51 | -$0.55 | -$0.47 | -$0.49 | -$0.49 |
| Operating cash flow | -$13.9M | -$17.3M | -$17.4M | -$19.5M | -$16.6M | -$12.3M | -$15.2M | -$20.5M |
| Free cash flow | -$14.0M | -$18.3M | -$18.2M | -$19.6M | -$17.1M | -$13.2M | -$15.5M | -$20.6M |
| Gross margin | — | — | — | — | — | — | — | — |
| Operating margin | — | — | — | — | — | — | — | — |
| Net margin | — | — | — | — | — | — | — | — |
Consensus revenue & EPS estimates and price targets will appear here once a forward-estimates data feed is connected.
| Date | Insider | Type | Shares | Price | Value | Filing |
|---|---|---|---|---|---|---|
| 2026-05-21 | Blume-Jensen Peter· President and CEO | Tax withholding | 13,729 | $1.79 | $24,574.91 | filing |
| 2026-05-18 | RA CAPITAL MANAGEMENT, LLC | Award | 9,366 | $0.00 | $0.00 | filing |
| 2026-05-18 | TOMSICEK MICHAEL JOHN | Award | 9,366 | $0.00 | $0.00 | filing |
| 2026-05-18 | Shacham Sharon | Award | 9,366 | $0.00 | $0.00 | filing |
| 2026-05-18 | Palani Santhosh | Award | 9,366 | $0.00 | $0.00 | filing |
| 2026-05-18 | Magovcevic Ivana | Award | 9,366 | $0.00 | $0.00 | filing |
| 2026-05-18 | DiRocco Derek | Award | 9,366 | $0.00 | $0.00 | filing |
| 2026-05-18 | BAUM CHARLES M | Award | 9,366 | $0.00 | $0.00 | filing |
| 2026-05-18 | Peterson Katharine· Chief Accounting Officer | Award | 14,227 | $0.00 | $0.00 | filing |
| 2026-05-18 | Mirza Mansoor Raza· Chief Medical Officer | Award | 38,817 | $0.00 | $0.00 | filing |
| 2026-05-18 | Miller Mary· Chief Legal Officer | Award | 49,830 | $0.00 | $0.00 | filing |
| 2026-05-18 | Levy Adam D.· Chief Financial Officer | Award | 46,167 | $0.00 | $0.00 | filing |
| 2026-05-18 | Gamelin Erick· Chief Development Officer | Award | 38,584 | $0.00 | $0.00 | filing |
| 2026-05-18 | Devroe Eric· Chief Operating Officer | Award | 72,981 | $0.00 | $0.00 | filing |
| 2026-05-18 | Blume-Jensen Peter· President and CEO | Award | 180,095 | $0.00 | $0.00 | filing |
| 2026-05-18 | Blume-Jensen Peter· President and CEO | Award | 72,706 | $0.00 | $0.00 | filing |
| 2026-05-14 | Blume-Jensen Peter· President and CEO | Tax withholding | 1,253 | $1.92 | $2,405.76 | filing |
| 2026-05-14 | Devroe Eric· Chief Operating Officer | Tax withholding | 613 | $1.92 | $1,176.96 | filing |
| 2026-05-14 | Blume-Jensen Peter· President and CEO | Tax withholding | 490 | $1.92 | $940.80 | filing |
| 2026-05-14 | Gamelin Erick· Chief Development Officer | Tax withholding | 404 | $1.92 | $775.68 | filing |
| 2026-05-14 | Miller Mary· Chief Legal Officer | Tax withholding | 184 | $1.92 | $353.28 | filing |
| 2026-05-14 | Peterson Katharine· Chief Accounting Officer | Tax withholding | 99 | $1.92 | $190.08 | filing |
| 2026-04-22 | RA CAPITAL MANAGEMENT, LLC | Award | 3,888,888 | $1.80 | $7.0M | filing |
| 2026-04-17 | Miller Mary· Chief Legal Officer | Tax withholding | 558 | $1.78 | $993.24 | filing |
| 2026-02-21 | Blume-Jensen Peter· President and CEO | Tax withholding | 14,265 | $1.53 | $21,825.45 | filing |
Showing the latest 25 transactions — full history in the linked SEC filings.
Fundamentals & filings from SEC EDGAR. Prices adjusted for splits & dividends. Not investment advice.